MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1599440-25-1]
UNSPSC
12352203
Hazard Statement
H302, H315, H319
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-gly-gly-phe-gly-nh-ch2-o-ch2cooh.html
Purity
99.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
Molecular Formula
C28H36N6O10
Molecular Weight
616.62
Precautions
H302, H315, H319
References & Citations
[1]Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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