Asperosaponin VI

Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities[1][2][3][4].

Product Specifications

CAS Number

[39524-08-8]

Product Name Alternative

Akebia saponin D

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; Apoptosis; Caspase; HIF/HIF Prolyl-Hydroxylase; p38 MAPK; PERK; PPAR

Type

Natural Products

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/asperosaponin-vi.html

Purity

99.62

Solubility

DMSO : ≥ 25 mg/mL

Smiles

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