Asperosaponin VI
Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities[1][2][3][4].
Product Specifications
CAS Number
39524-08-8
Product Name Alternative
Akebia saponin D
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; Apoptosis; Caspase; HIF/HIF Prolyl-Hydroxylase; p38 MAPK; PERK; PPAR
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/asperosaponin-vi.html
Purity
99.62
Solubility
DMSO : ≥ 25 mg/mL
Smiles
Molecular Formula
C47H76O18
Molecular Weight
929.10
Precautions
H302, H315, H319, H335
References & Citations
Dipsacus asper
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3
Available Sizes
Frequently Asked Questions
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