Vildagliptin
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].
Product Specifications
CAS Number
274901-16-5
Product Name Alternative
LAF237; NVP-LAF 237
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Dipeptidyl Peptidase; Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Vildagliptin.html
Purity
99.93
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O[C@@]1(C2)C[C@H]3C[C@H](C[C@]2(NCC(N4[C@H](C#N)CCC4)=O)C3)C1
Molecular Formula
C17H25N3O2
Molecular Weight
303.40
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
DPP-4
Available Sizes
Frequently Asked Questions
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