USP1-IN-2
Product Specifications
UNSPSC Description
USP1-IN-2 (Compound I-193) is a potent ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of less than about 50 nM[1].
Target Antigen
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp1-in-2.html
Solubility
DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1NC2=CN=C(C3=C(C(C)C)C(F)=CC=C3)N=C2N1CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4
Molecular Weight
510.49
References & Citations
[1]Alexandre Joseph Buckmelter, et al. Purinones as ubiquitin-specific protease 1 inhibitors. Patent US20170145012A1.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148099/USP1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148099/USP1-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2098212-05-4
Available Sizes
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