α-Carotene

α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables[1][2].

Product Specifications

CAS Number

[7488-99-5]

Product Name Alternative

MK-591

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/α-carotene.html

Purity

99.0

Solubility

DMSO : 1 mg/mL (ultrasonic; warming)

Smiles

CC1(C)[C@@H](/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)=CCC1

Molecular Formula

C40H56

Molecular Weight

536.87

References & Citations

[1]Bushway, R.J., et al. Determination of α- and β-carotene in fruit and vegetables by high performance liquid chromatography. Can. Inst. Food Sci. Technol. J. 15 (3), 165-169 (1982) .|[2]Liu YZ, et al. Alpha-carotene inhibits metastasis in Lewis lung carcinoma in vitro, and suppresses lungmetastasis and tumor growth in combination with taxol in tumor xenografted C57BL/6 mice. J Nutr Biochem. 2015 Jun;26 (6) :607-15.|[3]Murakoshi M, et al. Inhibitory effects of alpha-carotene on proliferation of the human neuroblastoma cell line GOTO. J Natl Cancer Inst. 1989 Nov 1;81 (21) :1649-52.