L-Ascorbic acid-13C-1
Product Specifications
UNSPSC Description
L-Ascorbic acid-13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
Target Antigen
Apoptosis; Calcium Channel; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB;Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-ascorbic-acid-13c-1.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]([C@]1([H])C(O)=[13C](C(O1)=O)O)O
Molecular Weight
177.12
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.;Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0166S2/L-Ascorbic-acid-13C-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0166S2/
Clinical Information
No Development Reported
CAS Number
178101-89-8
Available Sizes
Curated Selection
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