1,3-Dicaffeoylquinic acid

1,3-Dicaffeoylquinic acid is a caffeoylquinic acid derivative that exhibits antioxidant activity and radical scavenging activity.

Product Specifications

CAS Number

[19870-46-3]

Product Name Alternative

1,3-O-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; PI3K; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/1,3-Dicaffeoylquinic-acid.html

Purity

99.09

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@]1(OC(/C=C/C2=CC=C(O)C(O)=C2)=O)C[C@@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[C@H](O)[C@H](O)C1)O

Molecular Formula

C25H24O12

Molecular Weight

516.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang Z, et al. An LC-MS/MS method for simultaneous determination of 1,5-dicaffeoylquinic acid and 1-O-acetylbritannilactone in rat plasma and its application to a pharmacokinetic study.|[2]Xiao HB, et al. 1,5-dicaffeoylquinic acid protects primary neurons from amyloid β 1-42-induced apoptosis via PI3K/Akt signaling pathway. Chin Med J (Engl) . 2011 Sep;124 (17) :2628-35.|[3]Cao X, et al. 1, 5-Dicaffeoylquinic acid-mediated glutathione synthesis through activation of Nrf2 protects against OGD/reperfusion-induced oxidative stress in astrocytes. Brain Res. 2010 Aug 6;1347:142-8.