Difethialone

Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts[1].

Product Specifications

CAS Number

[104653-34-1]

Product Name Alternative

LM-2219

UNSPSC

12352005

Hazard Statement

H300, H310, H330, H360, H372, H410

Target

VD/VDR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/difethialone.html

Purity

99.84

Smiles

O=C1SC2=C(C(O)=C1C3C4=C(CC(C3)C5=CC=C(C6=CC=C(Br)C=C6)C=C5)C=CC=C4)C=CC=C2

Molecular Formula

C31H23BrO2S

Molecular Weight

539.48

Precautions

H300, H310, H330, H360, H372, H410

References & Citations

[1]Nahas K, et al. Difethialone (LM-2219) : a new anticoagulant rodenticide for use against warfarin-resistant and-susceptible strains of Rattus norvegicus and Mus musculus[C]//Annales de Recherches Veterinaires. 1989, 20 (2) : 159-164.