Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg (TFA)
Product Specifications
UNSPSC Description
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Ar TFA is a fluorogenic renin substrate based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP)[1].
Target Antigen
Angiotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/arg-glu-edans-ile-his-pro-phe-his-pro-phe-his-leu-val-ile-his-thr-lys-dabcyl-arg-tfa.html
Purity
98.75
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCC(NCCNC1=CC=CC2=C1C=CC=C2S(=O)(O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CNC=N3)C(N4[C@@H](CCC4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CNC=N6)C(N7[C@@H](CCC7)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%10=CNC=N%10)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCNC(C%11=CC=C(C=C%11)/N=N/C%12=CC=C(C=C%12)N(C)C)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N.OC(C(F)(F)F)=O
Molecular Weight
2778.12
References & Citations
[1]Katherine Paschalidou, et al. Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions. Biochem J. 2004 Sep 15;382(Pt 3):1031-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5123A/Arg-Glu-edans-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys-dabcyl-Arg-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5123A/Arg-Glu-edans-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys-dabcyl-Arg-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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