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Arg-Glu (edans) -Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (dabcyl) -Arg (TFA)

Selected Variant

HY-P5123A-01

Size: 5 mg

Arg-Glu (edans) -Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys (dabcyl) -Ar TFA is a fluorogenic renin substrate based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP) [1].

Product Specifications

UNSPSC

12352209

Target

Angiotensin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/arg-glu-edans-ile-his-pro-phe-his-pro-phe-his-leu-val-ile-his-thr-lys-dabcyl-arg-tfa.html

Purity

98.75

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CCC(NCCNC1=CC=CC2=C1C=CC=C2S(=O)(O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CNC=N3)C(N4[C@@H](CCC4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CNC=N6)C(N7[C@@H](CCC7)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%10=CNC=N%10)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCNC(C%11=CC=C(C=C%11)/N=N/C%12=CC=C(C=C%12)N(C)C)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N.OC(C(F)(F)F)=O

Molecular Formula

C131H180F3N37O26S

Molecular Weight

2778.12

References & Citations

[1]Katherine Paschalidou, et al. Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3- (7-methoxy-4-coumaryl) propionic acid with 2,4-dinitrophenyl groups at various positions. Biochem J. 2004 Sep 15;382 (Pt 3) :1031-8.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

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