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TTL rabbit pAb

TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al. 2003 [PubMed 14571137]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529) . Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]) .[supplied by OMIM, Mar 2008]

UniProt

Q8NG68

Swiss Prot

Q8NG68

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human TTL AA range: 160-210

Target

TTL

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Gene ID (Human)

150465

Available Sizes

Curated Selection

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