Bucumolol (hydrochloride)
Product Specifications
UNSPSC Description
Bucumolol hydrochloride is a β-adrenergic receptor antagonist that can slow heart rate (negative chronotropic effect) and reduce cardiac contractility (negative inotropic effect). Bucumolol hydrochloride has antiarrhythmic and local anesthetic activity and can be used in the study of cardiovascular diseases[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bucumolol-hydrochloride.html
Smiles
O=C1C=CC2=C(C=CC(OCC(CNC(C)(C)C)O)=C2O1)C.Cl
Molecular Weight
341.83
References & Citations
[1]Nakayama, Koichi, et al. Antiarrhythmic activity of dextro-and levo-isomers OF 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrochloride (bucumolol), a β-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs. The Japanese Journal of Pharmacology 29.6 (1979): 935-945.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122364/Bucumolol-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122364/
Clinical Information
No Development Reported
CAS Number
36556-75-9
Curated Selection
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