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9-Propenyladenine

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.

Product Specifications

CAS Number

[1446486-33-4]

Product Name Alternative

Mutagenic Impurity of Tenofovir Disoproxil; Tenofovir Impurity 2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Mutagenic-Impurity-of-Tenofovir-Disoproxil.html

Concentration

10mM

Purity

96.69

Solubility

DMSO : ≥ 29 mg/mL

Smiles

NC1=C2N=CN(/C=C/C)C2=NC=N1

Molecular Formula

C8H9N5

Molecular Weight

175.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Montgomery J A, et al., The Use of the Allyl Group as a Blocking Group for the Synthesis of N-Substituted Purines1[J]. The Journal of Organic Chemistry, 1965, 30 (9) : 3235-3236.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Available Sizes

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