KDM2B-IN-1
KDM2B-IN-1 (example 32) is a histone demethylase (kdm2b) inhibitor with an IC50 of 0.016 nM. KDM2B-IN-1 can be used for hyperproliferative diseases research[1].
Product Specifications
CAS Number
[1965248-33-2]
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kdm2b-in-1.html
Purity
99.19
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C1=CC=C2C(CCCC2)=C1)(N3C(N4CCN(C5CCC5)CC4)=NCC3)=O
Molecular Formula
C21H30N4O2S
Molecular Weight
402.55
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Brian K. Albrecht, et al. 4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors. Patent WO2016112251A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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