Recombinant Human MIP-4/CCL18 protein
Product Specifications
Background
Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell-mediated immunity responses.
Molecular Weight
Approximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 69 amino acids.
CAS Number
9000-83-3
Available Sizes
Curated Selection
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