COH34 analog 1
COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly (ADP-ribose) glycohydrolase (PARG) inhibitor[1].
Product Specifications
CAS Number
314248-24-3
UNSPSC
12352005
Target
Poly (ADP-ribose) Glycohydrolase (PARG)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/coh34-analog-1.html
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(C)C=C1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
Molecular Formula
C18H15NO3S
Molecular Weight
325.38
References & Citations
[1]Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5 (4) :eaav4340.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
