COH34 analog 1
COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly (ADP-ribose) glycohydrolase (PARG) inhibitor[1].
Product Specifications
CAS Number
314248-24-3
UNSPSC
12352005
Target
Poly (ADP-ribose) Glycohydrolase (PARG)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/coh34-analog-1.html
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(C)C=C1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O
Molecular Formula
C18H15NO3S
Molecular Weight
325.38
References & Citations
[1]Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5 (4) :eaav4340.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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