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COH34 analog 1

COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly (ADP-ribose) glycohydrolase (PARG) inhibitor[1].

Product Specifications

CAS Number

314248-24-3

UNSPSC

12352005

Target

Poly (ADP-ribose) Glycohydrolase (PARG)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/coh34-analog-1.html

Purity

98.75

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(C)C=C1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O

Molecular Formula

C18H15NO3S

Molecular Weight

325.38

References & Citations

[1]Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5 (4) :eaav4340.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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