CCK antagonist 1
CCK antagonist 1 (compound 3d) is a CCK antagonist with IC50s of 1.1 μM and 4 μM for CCK1 and CCK2, respectively. CCK antagonist 1 can be used for research of cancer and mental disease[1].
Product Specifications
CAS Number
[742116-45-6]
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cck-antagonist-1.html
Purity
99.96
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(CCC1=CNC2=C1C=CC=C2)NC3=C(C)N(C)N(C4=CC=CC=C4)C3=O
Molecular Formula
C22H22N4O2
Molecular Weight
374.44
References & Citations
[1]Eric Lattmann, et al. Novel ureido - and amido-pyrazolone derivatives. Patent WO2004106306A1.|[2]Lattmann E, et al. Synthesis and evaluation of N- (3-oxo-2,3-dihydro-1H-pyrazol-4-yl) -1H-indole-carboxamides as cholecystokinin antagonists. J Pharm Pharmacol. 2006 Mar;58 (3) :393-401.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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