CCK antagonist 1

CCK antagonist 1 (compound 3d) is a CCK antagonist with IC50s of 1.1 μM and 4 μM for CCK1 and CCK2, respectively. CCK antagonist 1 can be used for research of cancer and mental disease[1].

Product Specifications

CAS Number

[742116-45-6]

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cck-antagonist-1.html

Purity

99.96

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(CCC1=CNC2=C1C=CC=C2)NC3=C(C)N(C)N(C4=CC=CC=C4)C3=O

Molecular Formula

C22H22N4O2

Molecular Weight

374.44

References & Citations

[1]Eric Lattmann, et al. Novel ureido - and amido-pyrazolone derivatives. Patent WO2004106306A1.|[2]Lattmann E, et al. Synthesis and evaluation of N- (3-oxo-2,3-dihydro-1H-pyrazol-4-yl) -1H-indole-carboxamides as cholecystokinin antagonists. J Pharm Pharmacol. 2006 Mar;58 (3) :393-401.