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AM-92016 (hydrochloride)

AM-92016 hydrochloride is a specific blocker of rectifier potassium current (IK) . AM-92016 hydrochloride delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse thereby restricting the duration of the nerve impulse[1].

Product Specifications

CAS Number

133229-11-5

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/am-92016-hydrochloride.html

Concentration

10mM

Purity

99.28

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CS(=O)(NC1=CC=C(OCC(O)CN(CCC2=CC=C(Cl)C(Cl)=C2)C)C=C1)=O.Cl

Molecular Formula

C19H25Cl3N2O4S

Molecular Weight

483.84

References & Citations

[1]ConnorsSP, etal.Actions and mechanisms of action of novel analogues of sotalol on guinea-pig and rabbitventricular cells. Br J Pharmacol. 1992 Aug;106 (4) :958-65.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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