Pulsatilla saponin D

Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent[1][2][3][4].

Product Specifications

CAS Number

[68027-15-6]

Product Name Alternative

SB365; Hederacolchiside A

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pulsatilla-saponin-d.html

Purity

99.89

Solubility

DMSO : ≥ 39 mg/mL

Smiles

C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O[C@@](OC[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]4O)O)([H])O[C@@H]4CO)[C@@H]5O)([H])[C@@H]5O[C@@](O[C@@H](C)[C@H](O)[C@H]6O)([H])[C@@H]6O)C)(CC[C@@]2([H])[C@]3(C)CO)[C@@](C7=CC1)(CC[C@]8(C(O)=O)[C@@]7([H])CC(C)(C)CC8)C

Molecular Formula

C47H76O17

Molecular Weight

913.10

References & Citations

[1]Hong SW, et al. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. Carcinogenesis. 2013 Sep;34 (9) :2156-69.|[2]Son MK, et al. SB365, Pulsatilla saponin D suppresses proliferation and induces apoptosis of pancreatic cancer cells. Oncol Rep. 2013 Aug;30 (2) :801-8.|[3]Son MK, et al. SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway. Food Chem. 2013 Jan 1;136 (1) :26-33.|[4]Yong Kim, et al. Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana. Arch Pharm Res. 2004 Sep;27 (9) :915-8.