Hydrocortisone acetate

Hydrocortisone acetate (Hydrocortisone 21-acetate) is a corticosteroid used to reduce swelling, itching and pain caused by minor skin irritations or hemorrhoids[1].

Product Specifications

CAS Number

[50-03-3]

Product Name Alternative

Hydrocortisone 21-acetate; Cortisol 21-acetate

UNSPSC

12352211

Hazard Statement

H360, H373

Target

Endogenous Metabolite; Glucocorticoid Receptor

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Hydrocortisone-acetate.html

Concentration

10mM

Purity

99.39

Solubility

DMSO : ≥ 38 mg/mL|H2O : < 0.1 mg/mL

Smiles

C[C@@]12[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

Molecular Formula

C23H32O6

Molecular Weight

404.50

Precautions

H360, H373

References & Citations

[1]Jurand A. The effect of hydrocortisone acetate on the development of mouse embryos. J Embryol Exp Morphol. 1968 Nov;20 (3) :355-66. |[2]Levy AL, Waldmann TA. The effect of hydrocortisone on immunoglobulin metabolism. J Clin Invest. 1970 Sep;49 (9) :1679-84.