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Polyclonal Olig2 Antibody, Rabbit IgG

Polyclonal Olig2 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.<br> Gene Synonyms: Oligo2, bHLHe19, oligodendrocyte transcription factor 2.

Product Specifications

Background

The oligodendrocyte transcription factor 2 (Olig2) is a basic helixloophelix transcription factor which is highly expressed in the oligodendrocytelineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.<br> Zhang K, et al. Nat Commun. 2022;13(1):1423. doi: 10.1038/s4146702229068z.<br> Ono K, et al. Mol Cells. 2009;27(4):397401. doi: 10.1007/s1005900900672.<br> General Notes: FOR RESEARCH USE ONLY.

CAS Number

9007-83-4

Origin Species

Rabbit

Target

Olig2

Conjugation

Unconjugated

Tag

Rabbit IgG

Stability

Shipped at 20°C. Store at 20°C for 3 years; Shipped at 20°C. Store at 80°C for 5 years._x000D_ _x000D_Please avoid repeated freezethaw cycles.

Format

Liquid

Buffer

PBS, 50 mM Glycine, 50 mM Tris

Additives

40% glycerol

Shipping Conditions

Blue Ice

Storage Conditions

20°C

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