TP0586532
TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM) . TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1]. TP0586532 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2427584-96-9
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tp0586532.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@H](O)C1=NC=CN1CC2=NOC(C(C=C3)=CC=C3C#C[C@H]4[C@@]5([H])[C@]4([H])CN(C5)CCCC(O)=O)=C2
Molecular Formula
C26H28N4O4
Molecular Weight
460.52
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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