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Recombinant Human Interleukin-6 Receptor Subunit Alpha

Product Specifications

UniProt

P08887.1

Target

Leu20-Asp358

Purification

> 97 % by SDS-PAGE analyses.

Endotoxin

Less than 1 EU/ug of rHuIL-6 Rα as determined by LAL method.

Bioactivity

Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml.

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculated Molecular Weight

Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids.

Formulation

Lyophilized from 0.2 μm filtered concentrated solution in PBS.

Host or Source

Spodoptera frugiperda, Sf21 (baculovirus) .

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