SR-3677
Product Specifications
UNSPSC Description
SR-3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM.
Target Antigen
Autophagy; ROCK
Type
Reference compound
Related Pathways
Autophagy;Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SR-3677.html
Smiles
CN(C)CCOC1=C(NC(C2OC(C=CC=C3)=C3OC2)=O)C=CC(C4=CNN=C4)=C1
Molecular Weight
408.45
References & Citations
[1]Feng Y, et al. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem. 2008 Nov 13;51(21):6642-5.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13300/SR-3677-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13300/SR-3677-SDS-MedChemExpress.pdf
CAS Number
1072959-67-1
Available Sizes
Curated Selection
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