Hemokinin 1, human (TFA)
Product Specifications
UNSPSC Description
Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human TFA is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human TFA can produces an opioid-independent analgesia[1][2].
Target Antigen
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hemokinin-1-human-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
Molecular Weight
1185.40 (free base)
References & Citations
[1]Cai-Yun Fu, et al. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One|[2]Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135(1):266-74.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1198A/Hemokinin-1-human-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1198A/
Clinical Information
No Development Reported
Curated Selection
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