Sarmentosin
Sarmentosin is an activator of Nrf2. Sarmentosin inhibits mTOR signaling and induces autophagy-dependent apoptosis in human HCC cells[1].
Product Specifications
CAS Number
[71933-54-5]
Product Name Alternative
Sarmentosine; Sarmentosine (glycoside)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Keap1-Nrf2; mTOR
Type
Natural Products
Related Pathways
Apoptosis; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sarmentosin.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
N#C/C(CO)=C\CO[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O
Molecular Formula
C11H17NO7
Molecular Weight
275.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang Z, et al. Sarmentosin Induces Autophagy-dependent Apoptosis via Activation of Nrf2 in Hepatocellular Carcinoma. J Clin Transl Hepatol. 2023 Aug 28;11 (4) :863-876.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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