Sarmentosin
Sarmentosin is an activator of Nrf2. Sarmentosin inhibits mTOR signaling and induces autophagy-dependent apoptosis in human HCC cells[1].
Product Specifications
CAS Number
71933-54-5
Product Name Alternative
Sarmentosine; Sarmentosine (glycoside)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Keap1-Nrf2; mTOR
Type
Natural Products
Related Pathways
Apoptosis; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sarmentosin.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
N#C/C(CO)=C\CO[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O
Molecular Formula
C11H17NO7
Molecular Weight
275.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang Z, et al. Sarmentosin Induces Autophagy-dependent Apoptosis via Activation of Nrf2 in Hepatocellular Carcinoma. J Clin Transl Hepatol. 2023 Aug 28;11 (4) :863-876.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940178-100 1x 100 µL
CD50 (ICAM-3) (186-2G9), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741429-100 1x 100 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400178-100 1x 100 µL
CD50 (ICAM-3) (186-2G9), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680012-500 1x 500 µL
Tyrosinase (T311), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742391-100 1x 100 µL
GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details