AVJ16
Product Specifications
UNSPSC Description
AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 to inhibit the migration of H1299 cells with high endogenous IGF2BP1 expression. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation[1].
Target Antigen
Insulin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/avj16.html
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(CC1)C2=CC3=C(OCO3)C=C2)C4=CC=C(C=C4)CN5C(CO)=CC6=C5C=CC=C6
Molecular Weight
469.53
References & Citations
[1]Singh A, et al. Development of a Novel IGF2BP1 Inhibitor as Metastasis-Specific Therapeutic Agent[J]. European Journal of Cancer, 2022, 174: S104-S105.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144873/AVJ16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144873/AVJ16-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2775241-92-2
Available Sizes
Curated Selection
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