PROTAC SMARCA2 degrader-29
Product Specifications
UNSPSC Description
PROTAC SMARCA2 degrader-29 (Example 87) is a PROTAC SMARCA2 (BRM) degrader, with DC50 of 10-100 nM (BRM) and > 1 μM (BRG1, also known as SMARCA2) respectively[1].
Target Antigen
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-degrader-29.html
Smiles
CC(C)[C@@H](C(N1C[C@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)C4=CC(N5CCC(N6CCC(C7=CC8=C(C=C(C9=CC=CC=C9O)N=N8)S7)CC6)CC5)=NO4
Molecular Weight
875.11
References & Citations
[1]Matthew Netherton, et al. Compounds and uses thereof. Patent. WO2022240825
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168246/PROTAC-SMARCA2-degrader-29-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168246/
Clinical Information
No Development Reported
CAS Number
2865193-25-3
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