KT D606
Product Specifications
UNSPSC Description
KT D606 is an inhibitor of the PAK kinase family, with an IC50 value of 4 μM. KT D606 selectively blocks the proliferation of cancer cells transformed by oncogenic RAS mutants and can be used for research on RAS/PAK1-induced cancers[1].
Target Antigen
PAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kt-d606.html
Smiles
C[C@]12N3C4=C(C5=CC=CC=C53)C(C(NC6=O)CCCCCCCC7C8=C(C(N7)=O)C9=C%10C%11=C8C%12=CC=CC=C%12N%11[C@](C)([C@](O)(C%13)C(O)=O)O[C@@]%13([H])N%10C%14=CC=CC=C9%14)=C6C%15=C4N([C@](C[C@]2(O)C(O)=O)([H])O1)C%16=CC=CC=C%15%16
Molecular Weight
1003.06
References & Citations
[1]Nheu TV, et al. The K252a derivatives, inhibitors for the PAK/MLK kinase family selectively block the growth of RAS transformants. Cancer J. 2002 Jul-Aug;8(4):328-36.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164488/KT-D606-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164488/
Clinical Information
No Development Reported
CAS Number
1429063-06-8
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