BD1063 (dhydrochloride)
BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
Product Specifications
CAS Number
206996-13-6
UNSPSC
12352005
Hazard Statement
H319
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/BD1063_dhydrochloride.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1.Cl.Cl
Molecular Formula
C13H20Cl4N2
Molecular Weight
346.12
Precautions
H319
References & Citations
[1]Sabino V, et al. The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacology. 2009 May;34 (6) :1482-93.|[2]Cottone P, et al. Antagonism of sigma-1 receptors blocks compulsive-like eating. Neuropsychopharmacology. 2012 Nov;37 (12) :2593-604.|[3]Nieto FR, et al. Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice. J Pain. 2012 Nov;13 (11) :1107-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor
Available Sizes
Frequently Asked Questions
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