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Anti-Mouse L-Selectin/CD62L Antibody (Mel-14)

Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) is an anti-mouse L-Selectin/CD62L IgG2a monoclonal antibody. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can significantly inhibit the migration of T cells and B cells. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can block initial lymphocyte homing. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can be used for researches on inflammation, metabolic and infection conditions such as diabetes and parasitic infections[1][2][3][4].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

L-Selectin

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-l-selectin-cd62l-antibody-mel-14.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseL-Selectin/CD62LAntibody(Mel-14)]

Molecular Weight

(150 kDa)

References & Citations

[1]Serrano-Lopez J, et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. Elife. 2021 Apr 8;10:e66190.|[2]Ugur M, et al. Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks. Immunity. 2023 Aug 8;56 (8) :1778-1793.e10.|[3]Lepault F, et al. Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment. Eur J Immunol. 1995 Jun;25 (6) :1502-7.|[4]Laskay T, et al. In vivo blocking of L-selectin rescues BALB/c mice from fatal Leishmania major infection. Immunol Lett. 1997 Jun 1;57 (1-3) :89-91.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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