Scopine (hydrochloride)
Scopine hydrochloride is a metabolite of Scopolamine and brain-targeting compound. Scopine hydrochloride significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine hydrochloride can be used in targeted therapy research for brain gliomas[1].
Product Specifications
CAS Number
85700-55-6
Product Name Alternative
6,7-Epoxytropine hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Scopine-hydrochloride.html
Purity
99.69
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O[C@H]1C[C@H]2[C@@H]3O[C@@H]3[C@H](N2C)C1.[H]Cl
Molecular Formula
C8H14ClNO2
Molecular Weight
191.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang X, et al. Scopine as a novel brain-targeting moiety enhances the brain uptake of chlorambucil. Bioconjug Chem. 2014 Nov 19;25 (11) :2046-54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Citation 01
Anal Bioanal Chem. 2025 Jun;417 (14) :3169-3176.|Molecules. 2025 Oct 23;30 (21) :4170.
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