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Scopine (hydrochloride)

Scopine hydrochloride is a metabolite of Scopolamine and brain-targeting compound. Scopine hydrochloride significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine hydrochloride can be used in targeted therapy research for brain gliomas[1].

Product Specifications

CAS Number

85700-55-6

Product Name Alternative

6,7-Epoxytropine hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Scopine-hydrochloride.html

Purity

99.69

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O[C@H]1C[C@H]2[C@@H]3O[C@@H]3[C@H](N2C)C1.[H]Cl

Molecular Formula

C8H14ClNO2

Molecular Weight

191.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al. Scopine as a novel brain-targeting moiety enhances the brain uptake of chlorambucil. Bioconjug Chem. 2014 Nov 19;25 (11) :2046-54.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Citation 01

Anal Bioanal Chem. 2025 Jun;417 (14) :3169-3176.|Molecules. 2025 Oct 23;30 (21) :4170.

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