Aminopeptidase-IN-1
Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments[1].
Product Specifications
CAS Number
[374102-08-6]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aminopeptidase-in-1.html
Purity
98.25
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N)OC2=CC(O)=CC=C2C1C3=CC=C([N+]([O-])=O)C=C3)OCC
Molecular Formula
C18H16N2O6
Molecular Weight
356.33
Precautions
H315, H319
References & Citations
[1]Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57 (4) :1368-77.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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