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Aminopeptidase-IN-1

Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments[1].

Product Specifications

CAS Number

[374102-08-6]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Aminopeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aminopeptidase-in-1.html

Purity

98.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(N)OC2=CC(O)=CC=C2C1C3=CC=C([N+]([O-])=O)C=C3)OCC

Molecular Formula

C18H16N2O6

Molecular Weight

356.33

Precautions

H315, H319

References & Citations

[1]Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57 (4) :1368-77.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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