WRN inhibitor 3
WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2923009-48-5]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-3.html
Purity
99.54
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(C=CC=C2)=C2OCC3CC3)=CC=C1C(N[C@H]4CS(=O)(C=C4)=O)=O
Molecular Formula
C20H20N2O5S
Molecular Weight
400.45
References & Citations
[1]Ashley ADAMS, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. Patent. WO2023062575 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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