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WRN inhibitor 3

WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer[1].

Product Specifications

CAS Number

[2923009-48-5]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wrn-inhibitor-3.html

Purity

99.54

Solubility

10 mM in DMSO

Smiles

O=C1NC(C(C=CC=C2)=C2OCC3CC3)=CC=C1C(N[C@H]4CS(=O)(C=C4)=O)=O

Molecular Formula

C20H20N2O5S

Molecular Weight

400.45

References & Citations

[1]Ashley ADAMS, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. Patent. WO2023062575 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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