Pavinetant

Pavinetant (MLE-4901) is a neurokinin-3 receptor (NK3R) antagonist.

Product Specifications

CAS Number

[941690-55-7]

Product Name Alternative

MLE-4901; AZD2624; AZD4901

UNSPSC

12352005

Target

Neurokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/MLE-4901.html

Purity

99.83

Solubility

DMSO : ≥ 50 mg/mL

Smiles

CC[C@H](NC(C1=C(C=CC=C2)C2=NC(C3=CC=CC=C3)=C1NS(C)(=O)=O)=O)C4=CC=CC=C4

Molecular Formula

C26H25N3O3S

Molecular Weight

459.56

References & Citations

[1]Li Y, et al. In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P (450) enzyme identification, inhibition, and induction studies. Xenobiotica. 2010 Nov;40 (11) :721-9.