BIRT 377
BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1) . BIRT 377 also inhibits the production of IL-2 in vivo. BIRT 377 can be used for researching inflammatory and immune disorders[1].
Product Specifications
CAS Number
213211-10-0
UNSPSC
12352005
Target
Integrin; Interleukin Related
Type
Reference compound
Related Pathways
Cytoskeleton; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/birt-377.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C2=CC(Cl)=CC(Cl)=C2)C(N(C)[C@]1(C)CC3=CC=C(Br)C=C3)=O
Molecular Formula
C18H15BrCl2N2O2
Molecular Weight
442.13
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-2
Available Sizes
Frequently Asked Questions
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