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Recombinant Human TNFSF18 Protein (His Tag)

Product Specifications

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Abbreviation

TNFSF18

Synonyms

UNQ; PRO; Tnfsf; Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand; hGITRL; TNLG2A; AITRL; GITRL; TL6; TNFSF18; UNQ149; PRO175; Activation inducible TNF related ligand; AITR ligand; AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand; GITR ligand; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; MGC138237; TNF18; Tumor necrosis factor (ligand) superfamily member 18; Tumor necrosis factor ligand 2A; Tumor necrosis factor ligand superfamily member 18

UniProt

Q9UNG2

Accession Number

Q9UNG2

Expression System

Mammalian

Tag

C-His

Sequence

Glu52-Ser177

Field of Research

Immunology; Signal Transduction; Cancer

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.8 kDa

Observed Molecular Weight

25-30 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human

Available Sizes

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