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Adrenalone

Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM[1][2].

Product Specifications

CAS Number

[99-45-6]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/adrenalone.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

CNCC(C1=CC=C(O)C(O)=C1)=O

Molecular Formula

C9H11NO3

Molecular Weight

181.19

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]M GOLDSTEIN, et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081.|[2]Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108 (38) :15810-5.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B1308A/Adrenalone-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B1308A/Adrenalone-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Launched

Curated Selection

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