Adrenalone
Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM[1][2].
Product Specifications
CAS Number
99-45-6
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/adrenalone.html
Purity
90.0
Solubility
10 mM in DMSO
Smiles
CNCC(C1=CC=C(O)C(O)=C1)=O
Molecular Formula
C9H11NO3
Molecular Weight
181.19
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]M GOLDSTEIN, et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081.|[2]Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108 (38) :15810-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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