(R) -VX-11e
(R) -VX-11e (Compound 1) is an ERK2 inhibitor[1].
Product Specifications
CAS Number
[1680187-43-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-vx-11e.html
Purity
98.73
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(C2=NC(NC3=C(Cl)C=C(F)C=C3)=NC=C2C)=CN1)N[C@@H](CO)C4=CC=CC(Cl)=C4
Molecular Formula
C24H20Cl2FN5O2
Molecular Weight
500.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Vanderpool D, et al. Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors. Anal Biochem. 2015 Mar 15;473:46-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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