Brimarafenib
Brimarafenib is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor wtih antineoplastic effect[1].
Product Specifications
CAS Number
[1643326-82-2]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brimarafenibum.html
Purity
99.35
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
FC(C=C(C(F)=C1)F)=C1NC(N[C@H]2[C@@]3([H])[C@]2([H])OC4=CC=C(OC5=C6C(NC=C5)=NC(CC6)=O)C=C43)=O
Molecular Formula
C24H17F3N4O4
Molecular Weight
482.41
References & Citations
[1]Brimarafenibum (Brimarafenib) . WHO Drug Information, Vol. 37, No. 4, 2023.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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