Hydrocortisone buteprate

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation[1].

Product Specifications

CAS Number

[72590-77-3]

Product Name Alternative

Hydrocortisone probutate; HBP

UNSPSC

12352211

Hazard Statement

H315, H319, H320

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hydrocortisone-buteprate.html

Purity

99.29

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)OC(CCC)=O)=O)=O

Molecular Formula

C28H40O7

Molecular Weight

488.61

Precautions

H315, H319, H320

References & Citations

[1]Fölster-Holst R, et al. Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index. Pharmazie. 2016 Mar;71 (3) :115-21.