5'-Ethynyl-2'-deoxycytidine
5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL[1].
Product Specifications
CAS Number
69075-47-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/5-ethynyl-2-deoxycytidine.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C#CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(N=C1N)=O
Molecular Formula
C11H13N3O4
Molecular Weight
251.24
Precautions
H302, H315, H319, H335
References & Citations
[1]De Clercq E, et al., Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines. Mol Pharmacol. 1982 Jan;21 (1) :217-23.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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