5'-Ethynyl-2'-deoxycytidine

5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL[1].

Product Specifications

CAS Number

[69075-47-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/5-ethynyl-2-deoxycytidine.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C#CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(N=C1N)=O

Molecular Formula

C11H13N3O4

Molecular Weight

251.24

Precautions

H302, H315, H319, H335

References & Citations

[1]De Clercq E, et al., Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines. Mol Pharmacol. 1982 Jan;21 (1) :217-23.